Research / अनुसन्धान

There is minimal research on sickle cell disease in Nepal. Most papers published about sickle cell disease are limited to case reports. There has been no prevalence study of sickle cell disease in Nepal. More research is imperative to assess the burden of sickle cell disease and other hemoglobinopathies in Nepal.

This short bibliography is intended to highlight existing research on sickle cell disease and other hemoglobinopathies in Nepal. Both quantitative and qualitative research conducted by affiliates of Sickle Cell Nepal are under the process of publication. We will update this list periodically as more research gets published.

नेपालमा हँसिया रक्तकोश रोगको विषयमा धेरै कम अनुसन्धान भएको छ। धेरै जसो प्रकाशनहरुले खाली एक दुई वटा विरामीहरु बारे मात्र व्याख्या गर्छन्। नेपालमा हँसिया रक्तकोश रोग र अरु वंशानुगत रक्त रोगहरुका प्रभाव जान्नुको लागि अनुसन्धानको खाँचो छ।

तल दिइएको बिब्लियोग्राफी नेपालमा अहिले सम्म हँसिया रक्तकोश रोग र अरु वंशानुगत रक्त रोगहरु बारे गरिएको अनुसन्धानहरुको सानो सूचि हो। सिकल सेल नेपालको समन्वयकर्ताहरु द्वारा गरिएका मात्रात्मक र गुणात्मक अनुसन्धानहरु अहिले प्रकाशनको प्रक्रियामा छन्। थप अनुसन्धान प्रकाशित भए पछि हामीले यो सूचीलाई अपडेट गर्नेछौं।


Adhikari, RC, TB Shrestha, RC Shrestha, KP Parajuli, and S Dali
2003 Sickle Cell Disease – Case Reports. Journal of Nepal Medical Association 42: 36–38.

Amatya, A, R Choudhary, G Zeher, A Gurung, and A Rana
2007 Sickle Cell Anemia Complicated by Hepatitis E Infection in Pregnancy. Journal of Institute of Medicine 29(3): 53–55.

Brain, M.C., and F. Vella
1958 Haemoglobin-H Trait in a Nepalese Gurkha Woman. The Lancet 271(7013): 192–194.

Caetano, Catia P, Thirsa Kraaijenbrink, Nirmal M Tuladhar, et al.
2006 Nepalese Populations Show No Association between the Distribution of Malaria and Protective Alleles. Journal of Molecular and Genetic Medicine : An International Journal of Biomedical Research 2(1): 101–106.

Fornarino, Simona, Maria Pala, Vincenza Battaglia, et al.
2009 Mitochondrial and Y-Chromosome Diversity of the Tharus (Nepal): A Reservoir of Genetic Variation. BMC Evolutionary Biology 9(1): 154.

Modiano, G, G Morpurgo, L Terrenato, et al.
1991 Protection against Malaria Morbidity: Near-Fixation of the Alpha-Thalassemia Gene in a Nepalese Population. American Journal of Human Genetics 48(2): 390–397.

Sakai, Y, S Kobayashi, H Shibata, et al.
2000 Molecular Analysis of Alpha-Thalassemia in Nepal: Correlation with Malaria Endemicity. Journal of Human Genetics 45(3): 127–132.

Sherchand, O, R KC, S Majhi, M Lamsal, and N Baral
2013 Laboratory Parameters of Beta Thalassemia Patients Visiting BPKIHS as Diagnosed by Agarose Gel Electrophoresis. Journal of Institute of Medicine 35(1): 28–31.

Shrestha, A, and S Karki
2013 Analysis of Sickle Hemoglobin. Journal of Pathology of Nepal 3(6): 437–440.

Terrenato, L, S Shrestha, K A Dixit, et al.
1988 Decreased Malaria Morbidity in the Tharu People Compared to Sympatric Populations in Nepal. Annals of Tropical Medicine and Parasitology 82(1): 1–11.

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