There is minimal research on sickle cell disease in Nepal. Most papers published about sickle cell disease are limited to case reports. There has been no prevalence study of sickle cell disease in Nepal. More research is imperative to assess the burden of sickle cell disease and other hemoglobinopathies in Nepal.
This short bibliography is intended to highlight existing research on sickle cell disease and other hemoglobinopathies in Nepal. Both quantitative and qualitative research conducted by affiliates of Sickle Cell Nepal are under the process of publication. We will update this list periodically as more research gets published.
The Nepal Health Research Council has conducted a population based screening of sickle cell disease in Bardiya. The results are yet to be made public.
नेपालमा सिकल सेल रोगको विषयमा धेरै कम अनुसन्धान भएको छ। धेरै जसो प्रकाशनहरुले खाली एक दुई वटा विरामीहरु बारे मात्र व्याख्या गर्छन्। नेपालमा सिकल सेल रोग र अरु वंशानुगत रक्त रोगहरुका प्रभाव जान्नुको लागि अनुसन्धानको खाँचो छ।
तल दिइएको बिब्लियोग्राफी नेपालमा अहिले सम्म सिकल सेल रोग र अरु वंशानुगत रक्त रोगहरु बारे गरिएको अनुसन्धानहरुको सानो सूचि हो। सिकल सेल नेपालको समन्वयकर्ताहरु द्वारा गरिएका मात्रात्मक र गुणात्मक अनुसन्धानहरु अहिले प्रकाशनको प्रक्रियामा छन्। थप अनुसन्धान प्रकाशित भए पछि हामीले यो सूचीलाई अपडेट गर्नेछौं।
नेपाल स्वास्थ्य अनुसन्धान परिषदले बर्दिया जिल्लामा सिकल सेल रोगको स्क्रीनिंग गरेको छ, सो को नतिजा हाल सार्वजनिक गरिएको छैन।
Adhikari, RC, TB Shrestha, RC Shrestha, KP Parajuli, and S Dali
2003 Sickle Cell Disease – Case Reports. Journal of Nepal Medical Association 42: 36–38.
Amatya, A, R Choudhary, G Zeher, A Gurung, and A Rana
2007 Sickle Cell Anemia Complicated by Hepatitis E Infection in Pregnancy. Journal of Institute of Medicine 29(3): 53–55.
Brain, M.C., and F. Vella
1958 Haemoglobin-H Trait in a Nepalese Gurkha Woman. The Lancet 271(7013): 192–194.
Caetano, Catia P, Thirsa Kraaijenbrink, Nirmal M Tuladhar, et al.
2006 Nepalese Populations Show No Association between the Distribution of Malaria and Protective Alleles. Journal of Molecular and Genetic Medicine : An International Journal of Biomedical Research 2(1): 101–106.
Fornarino, Simona, Maria Pala, Vincenza Battaglia, et al.
2009 Mitochondrial and Y-Chromosome Diversity of the Tharus (Nepal): A Reservoir of Genetic Variation. BMC Evolutionary Biology 9(1): 154.
Gautam, Narayan, et al.
2019 Glucose 6 phosphate dehydrogenase deficiency and hemoglobinopathy in South Western Region Nepal: a boon or burden. BMC research notes 12(1):1-6.
Jha, R.
2015 Distribution of hemoglobinopathies in patients presenting for electrophoresis and comparison of result with High performance liquid chromatography. Journal of Pathology of Nepal 5(10):850-858.
Marchand M, Gill C, Malhotra AK, et al.
2017 The Assessment and Sustainable Management of Sickle Cell Disease in the Indigenous Tharu Population of Nepal. Hemoglobin 41:278-82.
Modiano, G, G Morpurgo, L Terrenato, et al.
1991 Protection against Malaria Morbidity: Near-Fixation of the Alpha-Thalassemia Gene in a Nepalese Population. American Journal of Human Genetics 48(2): 390–397.
Pande R, Ghimire PG, Chand PB.
2019 Sickle cell disease in Western Nepal. Nepal. Journal Of Medical Sciences 4:15-9.
Sakai, Y, S Kobayashi, H Shibata, et al.
2000 Molecular Analysis of Alpha-Thalassemia in Nepal: Correlation with Malaria Endemicity. Journal of Human Genetics 45(3): 127–132.
Sherchand, O, R KC, S Majhi, M Lamsal, and N Baral
2013 Laboratory Parameters of Beta Thalassemia Patients Visiting BPKIHS as Diagnosed by Agarose Gel Electrophoresis. Journal of Institute of Medicine 35(1): 28–31.
Shrestha, A, and S Karki
2013 Analysis of Sickle Hemoglobin. Journal of Pathology of Nepal 3(6): 437–440.
Terrenato, L, S Shrestha, K A Dixit, et al.
1988 Decreased Malaria Morbidity in the Tharu People Compared to Sympatric Populations in Nepal. Annals of Tropical Medicine and Parasitology 82(1): 1–11.
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